A centerfire cartridge is a cartridge with a primer located in the center of the cartridge case head. Unlike rimfire cartridges, the primer is a separate and replaceable component. Centerfire cartridges have supplanted the rimfire variety in all but the smallest cartridge sizes. With the exception of a few .17 caliber and .22 caliber pistol and rifle cartridges, small-bore shotgun cartridges (intended for pest-control), and a handful of antique, mostly obsolete cartridges, almost all pistol, rifle, and shotgun ammunition used today is centerfire. Shop through the top ammunition manufacturers in the industry including Hornady, Winchester, Federal, Remington and Barnes. Buy 10 units and get 5% off.